Palo Alto Networks and Google Cloud

Apr 22, 2026
6 minutes

Expand Strategic Collaboration to Secure the AI Enterprise

The transition from generative AI to agentic AI represents one of the most significant shifts in the history of enterprise technology. As organizations move from simple chatbots to autonomous agents that can execute business processes, the attack surface isn't just changing, it's exploding.

At Google Cloud Next 2026 in Las Vegas, Palo Alto Networks is proud to announce a series of groundbreaking integrations with Google Cloud. These innovations are designed to do more than just monitor the new AI-driven landscape; they are built to secure it by design. AI deployment is currently outpacing AI governance. By embedding our security platform into Google Cloud’s infrastructure, we are giving today’s enterprises the foundation to become the autonomous organizations of tomorrow.

Here is a look at the four major milestones of our partnership being unveiled this week.

Secure AI Agents with Google Cloud + Prisma AIRS

As autonomous AI agents become the new enterprise standard, security can no longer be an afterthought; it must be architectural. By integrating Prisma AIRS™ natively with Google Cloud Gemini Enterprise Agent Platform, we provide the proactive defenses required to govern complex agentic workflows. This integration ensures that as you scale your autonomous workforce, your security scales with it, providing comprehensive operational integrity without hindering the speed of innovation.

We are delivering capabilities across three critical pillars:

  • Protecting Agent-Specific Runtime Risks: In an agentic ecosystem, the primary risk is unauthorized or a destructive action taken by the AI agents themselves. Prisma AIRS secures the "agent-to-tool" interface, preventing poisoned context from triggering malicious scripts or destructive actions. The solution monitors agent execution in real-time, so agents cannot leak sensitive credentials or tool schemas, maintaining the boundary between agents and their access to enterprise data.
  • Securing the GenAI Application Surface: Modern AI applications and agents require a secure-by-design approach. Prisma AIRS AI Runtime Security™ provides prevention of more than 30 adversarial prompt injection and jailbreak techniques, as well as malicious code and URLs within LLM outputs. Prisma AIRS utilizes over 1,000 predefined patterns out of the box and ML-powered Enterprise DLP to stop sensitive data leakage.
  • Enforcing Enterprise AI Safety and Grounding: Trust in AI is built on the consistency and safety of its output. Prisma AIRS allows organizations to define safety policies in natural language and filter toxic content across eight distinct categories to protect brand reputation. Using contextual grounding, Prisma AIRS can prevent misleading outputs that contradict internal RAG data, keeping agents tied to real facts.

This integration ensures that as you scale your autonomous workforce, your security posture scales with it, providing operational integrity without hindering the speed of innovation.

Security-as-Code for Prisma AIRS Integration with Application Design Center (ADC)

The traditional bolt-on approach to security is no longer viable in a cloud-first world. Google Cloud’s Application Design Center (ADC) is revolutionizing how applications are built, using an intuitive canvas and natural language via Gemini Code Assist.

Palo Alto Networks is announcing that it will be published as a template within the Application Design Center, providing more capabilities to engineering teams:

  • Drag-and-Drop Security – Visually "snap" VM-Series firewalls and Prisma AIRS AI protections directly into network flows.
  • AI-Driven Architecture – Use natural language prompts to generate secure-by-default, multiregion architectures.
  • Simultaneous Deployment – Deploy entire application stacks and security services in a single, unified workflow, ensuring protection is present from the very first minute of deployment.

Zero-Day Protection at Scale with Advanced Malware Sandboxing for Google Cloud NGFW Enterprise

The battle against malware has shifted to the cloud. Modern attacks are faster, more evasive and capable of bypassing traditional defenses.

That is why we are excited to announce Advanced WildFire®, powered by Palo Alto Networks, natively integrated into Google Cloud NGFW Enterprise, delivering AI-driven malware prevention directly within Google Cloud environments.

This integration embeds inline sandboxing and real-time threat intelligence directly into Google Cloud’s distributed firewall to stop advanced and unknown threats before they impact workloads, enabling:

  • Secure Detonation – Suspicious files are safely executed in a controlled sandbox environment to uncover hidden and unknown threats.
  • Inline Traffic Inspection – Inbound and outbound traffic is analyzed in real time to prevent lateral movement of malicious payloads across cloud environments.
  • AI-Driven Threat Prevention – Leverages global threat intelligence by Palo Alto Networks to block zero-day threats before they compromise workloads.

With Advanced WildFire embedded directly into Google Cloud NGFW Enterprise, organizations can extend consistent protection across their cloud infrastructure while maintaining operational simplicity.

Cloud NGFW Enterprise Advanced Malware Sandboxing will be available in Public Preview soon.

Defining the Future with the Google Cloud Marketplace

Palo Alto Networks has joined the Google Cloud Marketplace Agent-as-a-Service as a launch partner to introduce the Prisma AIRS Model Security agent. Operating as an Agent-as-a-Service, this solution scans AI models for vulnerabilities and policy noncompliance before they reach production.

Available in the Agent Gallery inside Gemini Enterprise, this marketplace offering runs entirely within the customer’s own Google Cloud environment, providing both new and existing Prisma AIRS users a seamless and simple deployment experience inside Gemini Enterprise.

Securing AI Innovation at Scale

The collaboration between Palo Alto Networks and Google Cloud is built on a shared vision: Security should be an accelerator for innovation, not a bottleneck. As we look toward the future of the AI-powered enterprise, our commitment remains to provide the most robust, platform-driven security for every workload, every agent and every interaction.

Want to see these integrations in action? Contact your Palo Alto Networks representative to learn more about how we are securing the future of the cloud together. If you’re attending Google Cloud Next 2026, join us at these sponsored sessions:


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